Ultra City Smiths

Tom Waits

The Narrator (voice)

Jimmi Simpson

Detective David Mills (voice)

Da'Vine Joy Randolph

Detective Gail Johnson (voice)

John C. Reilly

Donovan Smith (voice)

Bebe Neuwirth

Lady Andrea The Giant (voice)

Melissa Villaseñor

Sister Mary Margaret (voice)

Kurtwood Smith

Carpenter K. Smith (voice)

Tim Heidecker

Mayor Kevin De Maximum (voice)

Chris Conrad

Detective Nico Onasis (voice)

Julian Barratt

The Most Dangerous Man in the World (voice)

Kristen Bell

Donella Pecker (voice)

Luis Guzmán

Rodrigo Smalls (voice)

Sunita Mani

Detective Jaya Mukherjee (voice)

Caleb McLaughlin

Trevor Johnson (voice)

Tim Meadows

Jeff Thumb (voice)

Terry O'Quinn

Captain Krieger (voice)

Dax Shepard

Chris Pecker (voice)

Debra Winger

Trish McSapphire (voice)

Jason Mantzoukas

Tim Snodgrass (voice)

Hana Mae Lee

Passerby 1 (voice)

Alia Shawkat

Woman's Voice (voice)

Damon Herriman

First Flophouse Resident (voice)

Mike O'Connell

Anchor Man (voice)

Jim Becker

34th Street Chuck (voice)

Antoine McKay

Chinatown Devin / 254 Bouncer (voice)

John Moxley

Second Motherless Three / Fourth Young Hustler (voice)

Tony Fitzpatrick

Promoter Tip Snarski / Policeman Driver (voice)

Peter Moxley

Third Motherless Three / Young Hustler (voice)

Jermaine Fowler

TMZ Operator / Second Young Hustler (voice)

Dana DeLorenzo

Sissy Smith / Voice on Earpiece (voice)

Valerie Azlynn

Space Bitch (voice)